Hello my daughter suffers from sever acne policy s tic ovaries since 12 she will be 14 in May Last year she was put on antibiotics followed by roaccutane For 41/2 to 5 months with azythromicine antibiotics she started on 20 mg her skin got worst than ever Then to 40 mg she suffered with excessive drying conditions nose bleeds lips cracking One day it was 17 degrees outside only her hands were exposed she burnt really bad Eventually there was improvement we stopped the medicine two months later it slowly returned worse than ever then she was put on spironolactone and metformin for couple of months and then stopped after on yasmin pill her skin was just getting so bad we saw yet another opinion and he put her on sjteroid 25mg daily for a week then 20 mg for second week lastly 15 for further week together restart of roaccutane (A year after stopping the last one) 20mg per day for two months then to be reduced to 10 mg for further 10 months she has also been put on trimethoprim 200 mg twice daily for 8 weeks from today She has just had an HERBST appliance fixed into her mouth as well which is due to come off in 12 months ( normally they fix this appliance from age 10 to 12 and my daughter is almost 14 the reason being is that the appliance is meant to bring the jaw forward to correct an overbite rather than to love two adult teeth which was an alternative solution ) Ian so confused and scared that my dafter is going to suffer more with all the she has tried and still trying Will the new dose and combine medication harm her growth then as a result will it affect the way the HERBST appliance would not be effective in doing what it s meant to do Will she stay short Will her bones be effected In June she is meant to go on a two weeks school trip in a hot climate iam so afraid that she will burn so is she ( even though her dose will be reduced to 10 mg two weeks prior her trip) I m not even sure if she s on the right dose she weighs 55 kg Please help she is suffering so long and so am I