Hello, There is no need to take enzyme supplement unless you have pancreatic insufficiency. I think you may be suffering from post cholicystectomy syndrome with GERD. Use tablet nexium before breakfast for one week. elevate the head end of bed while sleeping. Avoid spicy food and alcohol avoid smoking and caffeine drinks. Use soft diet with probiotics. if symptoms not improved please consult your gastroentrologist he will do upper GI endoscopy, serum amylase and lipase then treat you accordingly. Hope I have answered your query. Take care Regards, Dr. Penchila Prasad Kandikattu , Internal Medicine Specialist