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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Treatment For Esophageal Candidiasis

hello, m madhavi, intern at JLN hospital, my father is having dull pain at right hypochondriac and periumblical region off and on since six months. pain was prominent before meals.endoscopy was done which revealed esophageal candidiasis and fluconazole*14 days OD was given but pain is still persisting and increasing in frequency. plz guide me about the illness: diagnosis and treatment.
posted on Thu, 13 Mar 2014
Twitter Tue, 14 Jun 2016 Answered on
Twitter Tue, 14 Jun 2016 Last reviewed on
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Infectious Diseases Specialist,  's  Response
hi
Welcome to HCM
i had gone through your father's history and i can understand your concern towards your dad Madavi,
Candidiasis is a fungal infection caused by yeasts from the genus Candida. Candida albicans is the predominant cause of the disease.

Esophageal candidiasis
Patients with esophageal candidiasis may be asymptomatic or may have 1 or more of the following symptoms:

Normal oral mucosa (>50% of patients)
Dysphagia
Odynophagia
Retrosternal pain
Epigastric pain
Nausea and vomiting

Treatment
1 Esophagial Candidiasis requires systemic therapy with fluconazole for 14-
21 days.
2 Parenteral therapy with fluconazole may be required initially if the patient
is unable to take oral medications.
3 Daily suppressive antifungal therapy with fluconazole 100-200 mg/d is
effective for preventing recurrent episodes, but it should be used only if
the recurrences become frequent or are associated with malnutrition due to
poor oral intake and wasting syndrome.
4 Recommended alternatives for fluconazole-refractory disease include itraconazole, voriconazole, caspofungin, micafungin, anidulafungin, and amphotericin B.

I hope i have cleared your query
thank you
take care

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Suggest Treatment For Esophageal Candidiasis

hi Welcome to HCM i had gone through your father s history and i can understand your concern towards your dad Madavi, Candidiasis is a fungal infection caused by yeasts from the genus Candida. Candida albicans is the predominant cause of the disease. Esophageal candidiasis Patients with esophageal candidiasis may be asymptomatic or may have 1 or more of the following symptoms: Normal oral mucosa ( 50% of patients) Dysphagia Odynophagia Retrosternal pain Epigastric pain Nausea and vomiting Treatment 1 Esophagial Candidiasis requires systemic therapy with fluconazole for 14- 21 days. 2 Parenteral therapy with fluconazole may be required initially if the patient is unable to take oral medications. 3 Daily suppressive antifungal therapy with fluconazole 100-200 mg/d is effective for preventing recurrent episodes, but it should be used only if the recurrences become frequent or are associated with malnutrition due to poor oral intake and wasting syndrome. 4 Recommended alternatives for fluconazole-refractory disease include itraconazole, voriconazole, caspofungin, micafungin, anidulafungin, and amphotericin B. I hope i have cleared your query thank you take care