Hello dear Understand your concern Exact cause of fibromygia flare is not known but in your case it could be due to Genetic predisposition, Defect in dopamine and serotonin pathways in brain, Excessive stress and depression and Psychological disturbance Better to consult the rheumatologist to confirm the diagnosis. Diagnosis will be done on the clinical examination and detailed history. Drug that help to reduce pain: Tramadol, duloxentine and pregabline can be usd Cognitive behavioral therapy, Avoid negative self talk and behavior Be creative and learn new things, Spends more time with family and friends. Life style changes Acupuncture therapy, Regular yoga Relaxation therapy: whole body massage and breathing technique in fresh air, Bath in salted water Maintain weight according to normal BMI, Take healthy diet. Hope this may help you Best regards Dr. Sagar