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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Treatment For Lump On Testicle, Raised LDH And AST Levels

I have HCG in my seaman detectable on a hompe pregnancy test.. every time my wife and i have sex she is showing positive pregnancy the following day. how is this possible. i have been to the dr, i have a lump on my testicle that has been scanned and had some more blood work today which is inconclusive i do have raised LDH and AST levels is this related. i need to find out what is going on with my body.
Wed, 16 Sep 2015
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General & Family Physician 's  Response
Hi & Welcome to HCM.
I appreciate your concern for the presence of detectable hCG in your semen analysis with positive pregnancy test immediately following the sexual activity.

After having gone through the problem described in your query I am of the opinion that you seem to be having the testicular lump as a cancer referred to as germ cell tumor or choriocarcinoma.

It produces human chorionic gonadotropin (the main hormone actually produced by the placenta during pregnancy) which is secreted in the semen and hence the home pregnancy test is positive without having actual pregnancy.

It also produces a tumor marker called as Alpha-fetoprotein (AFP)
The raised enzymes like LDH & AST are also associated with the tumor which may indicate the spread of the disease to the liver until proved other wise.

In view of the above explanation, I would advise you to consult an oncologist for proper evaluation and to conduct additional lab tests such as Alpha fetoprotein, CT scan, Liver function tests to confirm the diagnosis.

The standard treatment for testicular choriocarcinoma include 4 cycles of chemotherapy (Bleomycin+Etoposide+Cisplatin).

Hope to have answered your query.

Wishing you best of your health.
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Suggest Treatment For Lump On Testicle, Raised LDH And AST Levels

Hi & Welcome to HCM. I appreciate your concern for the presence of detectable hCG in your semen analysis with positive pregnancy test immediately following the sexual activity. After having gone through the problem described in your query I am of the opinion that you seem to be having the testicular lump as a cancer referred to as germ cell tumor or choriocarcinoma. It produces human chorionic gonadotropin (the main hormone actually produced by the placenta during pregnancy) which is secreted in the semen and hence the home pregnancy test is positive without having actual pregnancy. It also produces a tumor marker called as Alpha-fetoprotein (AFP) The raised enzymes like LDH & AST are also associated with the tumor which may indicate the spread of the disease to the liver until proved other wise. In view of the above explanation, I would advise you to consult an oncologist for proper evaluation and to conduct additional lab tests such as Alpha fetoprotein, CT scan, Liver function tests to confirm the diagnosis. The standard treatment for testicular choriocarcinoma include 4 cycles of chemotherapy (Bleomycin+Etoposide+Cisplatin). Hope to have answered your query. Wishing you best of your health.