Hi, thanks for the query; How old is your mother? Whether she is a diagnosed case of hypothyroidism, diabetes, hypertension (based on blood tests, symptoms & physical examination by a qualified doctor) & hence taking all these medications under proper medical supervision? Also, whether she is constantly troubled by various poorly explained physical symptoms like indigestion, belching, gas, menstrual problems, frequent headaches, sleeping difficulties with requirements of sleeping pills like alprazolam, headaches, body pains etc.? If it is so, then your mother may be in fact suffering from Depression. Too many times depression tends to occur with diabetes, blood pressure problems & thyroid problems & often gets undiagnosed, untreated with a poor quality of life. Consult your GP/Psychiatrist for assessment of depression, use of drug like Daxid, Nexito etc. to treat her symptoms or get back to me for further assistance Hope this helps; good luck