**
1. Low bone mineral density (BMD) is common in
sickle cell disease patients due to erythropoietic
stress and consequent
bone marrow hyperplasia, thus preventive aspect is initiated:
. Calcium intake; 1.0-1.5 g per day [banana, jack fruit, grapes,coriander, raisins, milk, green vegetables, lemon,mint,papaya,amla,guava,pineapple,turnip,tomato, apple,orange.
ii. Moderate Vitamin D intake: 400-800 IU per day or
calcitriol 0.25~g/day
[ carot, beetroot,spianch,radish,mint,amalaki rasayan,soyabean,cucumber, cabbage,vitamin D fortified: pineapple/yogurt/milk/dry mushroom/banana/ cod liver oil/sunshine.
iii. Moderate Phoshorus intake: cheese,peanut butter,chicken,nuts,caramel, whole grain bread.
iv. Avoidance of alcohol, cigarette, tobacco.
v. Periodic assessment of skeletal status and bone mineral.
vi. Single Drug which is extremely helpful is 'Shatavari' which can be explained with the help of its active chemical constituent- Steroidal Saponins which are Phytoestrogens. Phytoestrogens acts as SERM's [selective estrogen receptors modulators] and stimulate osteoblastosis ans supress osteoclastosis and thus help in preventing bone loss.
Dose: Shatavari Churan [shatavari powder]: 6gm/day [thrice daily with milk] for 10 weeks
vii. Prescription Medicine which are effective in your condition is/are:
. BONTON [Vasu], REOSTEO [Himalaya]: