A horrible and life changing event happened a year ago. My professional career subsequently was also damaged and eventually lost as well, and depression set in. I have been presenting many of the symptoms associated with an lg-G4 related disease starting with persistent non responsive cellulitis two years ago, lately some vision changes have happened, sudden blurriness on and off, and I ve had infections that start from scratches and so on that I ve never had to deal with them being infected so easily before, everything to me seems to indicate a compromised immune system from some underlying cause, and I was thinking that an autoimmune disorder may have been latent and was triggered by the sequence of events in my life leading to this point. Could that have happened? i have developed what I believed to be just more epydimitis around two years ago in my right testicle, and didn t go get it checked out. Then for around a year or so while going through all that depression and such, it kept almost going away then returning again with the whole right side of the scroum painfully swollen all the way up my spermatochord. It was hard to determine if the lump was there because the gonad was so painful. I think i even went to the emergency room fearing testicular torsion, or some complication from the bilateral inguinal hernia op I had back then. I think I went on antibiotics and the swelling almost vanish, but the little anomaly remained, and it wasn t painful to palpate, so I went on with life. But of late, I ve been having lots of trouble with this phenomena, so i started down the road of the causation as possible trauma from to much sex, bacteria, it is not likely an std since I ve been with the same person for ten years, TB? Then the thought of it being a fiborous growth that wasn t a malignancy, but a pseudo tumor just above the epididymis on my right testicle came to mind. It could have originated by any number of things... I was once diagnosed in my twenties with epididymitis and have had that come and go since then, and now I m fifty, so it didn t seem all that bad at first. That could have been a mistaken diagnosis back then too....?? But with my health being dragged down over the past year, and then developing a fever, I got started figuring out what resources there were for broke people like me. I saw a family doctor who lined me up for an ultrasound with the results being interpreted as not being cancerous. There was no culture done and a 14 day course of Bactrim only lessened the cellulitis but seemed to aggrivate the possible pseudo tumor that could be associated with that rare immunodeficiency, or it could actually be cancer. I am just now getting back to myself again, but am penniless at this time for tests, and not a clue what medicaid will do, but these issues are all temporary and I ll find out. When I talked to the doctor about all the possibilities I had been pontificating with, I was only going for a discussion that would leave me feeling like I had a better game plan. I was figuring that if it was testicular cancer, I would likely have had bigger problems by now, but that s the only reasoning i was going on. All this could be sequelae from what I have had to endure over the last couple years too?? I m not comfortable being my own MD and hoped to talk about it with her... I have no idea if the doctor even knew if there was a lab here that would check my t-leucocytes for the typical mRNA coding that affects Lg-G4 immunoglobulins or not. She gave me a blank look, so I just wrote it down with the idea that she would naturally look it up herself for more information. One more visit and with empty feelings, and I ll need to figure out how to be assigned a different doctor, perhaps a Rheumatologist, or some other good open minded specialist without any career fit the money that I always relied upon. My visits have been about my depression and having some forward progress with the cellulitis, but I still had a cough, no more fever, and that painful mass that is about two centimeters around and smooth and goes from hard to bring painful and softer as it is now. She had given me citalopram for depression, and the Bactrim from the first visit has been completed, so this time she wanted to try a course of Azithrommycin. I got some claritin along with a small dosage of a blood pressure medicine this time too. The results of the ultrasound felt like a box got checked to me, as i want explanations. Besides, i have no idea who interpreted it, and since a correct interpretation of that ultrasound is hinged on the expertise of a technician I don t know, and the interpretation of another doctor I don t know, it s pretty rough depending on them for accuracy, What is your opinion on my statements above? By the way, the sri has ugly effects on my mind set so I stopped its use. My ADHD has proven through the years, to respond better on a dopamine reuptake inhibitor. But that s a conversation for a different time. Thank you for the time spent to ponder this with me. Most respectfully, Patrick