Suggest Treatment For Severe Depression, Fatigue And Anxiety

I stopped taking Synthyroid a few years ago after taking it for 25 years. I lost alot of hair, was depressed and had been on effexor for about 7 years, but I properly weaned off it, as it stopped working. The doctors started increasing the dosage of synthrod after about 20 years. Also, after starting synthroid my stomach hurt if I ate a scrambled or fried egg hours after taking the Synthyroid. First question, should I try the new thyroid medication? Not sure of the name, I think it starts with a T. I have tried all kinds of antidepressants and thought I should detox myself of these medications. Now I think I may need to take something for the constant depression, anxiety and fatigue. I am 46, 5 5 and about 125 lbs (anglo). Any ideas appreciated.