Hi, Thanks for writing in. Sorry to hear about stage 4 renal cell cancer in your mother. Since her cancer has spread to lungs and breast, therefore curative treatment is difficult. Thallix and interferon should be taken as suggested to control the further progression of disease. Please discuss with the oncologist if she should be given radiation therapy to control the disease progression and whether she is getting adequate pain relief. Additional pain relief medicines like opioids can be added when he develops bouts of sudden pain. In stage 4 disease patients can survive for 2 years with good treatment and supportive care. Therefore if he is able to maintain her general condition then she will be able to survive longer. Please give attention to her nutrition and give more proteins. She should also drink adequate water and fresh juices at frequent intervals to keep her hydrated. Please do not worry.