Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties
125 Doctors Online

By proceeding, I accept the Terms and Conditions

Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

HCM Blog Instant Access to Doctors
HCM BlogQuestions Answered
HCM Blog Satisfaction

Suggest Treatment To Regulate High Blood Sugar Levels

Hello, One of my Thalassaemia Major pre-pubertal patient taking 60 units of (mixtard)insulin daily,still shows RBS levels above 300mg/di ! How do I bring down his elevated blood sugar levels? Thank you for your time, Dr.Chalam, Male Maldives.                                                                  
posted on Thu, 13 Mar 2014
Twitter Sat, 27 Sep 2014 Answered on
Twitter Mon, 29 Sep 2014 Last reviewed on
Report Abuse
General & Family Physician,  's  Response
Hello Dr Chalam,
I am a Diabetologist working in Bangalore India,
From my experience these prepubertal patients with thalassemia major with secondary diabetes tend to have high levels of insulin resistance due to deposition of iron in the liver and other organs apart from the resistance due to hormonal changes. Due to this their daily requirements of insulin goes very high in relation to weight. You may need to switch to basal bolus regimen for him is what I feel. We have tried small doses of Metformin in some of these patients and had improvement in control. Although there is not much evidence on such use of Metformin. Ofourse consider iron chelation and discussion with the hematology team.
Hope this helps.
All the best.
I find this answer helpful
Disclaimer: These answers are for your information only and not intended to replace your relationship with your treating physician.
This is a short, free answer. For a more detailed, immediate answer, try our premium service [Sample answer]
Share on
 

Related questions you may be interested in


Loading Online Doctors....
Suggest Treatment To Regulate High Blood Sugar Levels

Hello Dr Chalam, I am a Diabetologist working in Bangalore India, From my experience these prepubertal patients with thalassemia major with secondary diabetes tend to have high levels of insulin resistance due to deposition of iron in the liver and other organs apart from the resistance due to hormonal changes. Due to this their daily requirements of insulin goes very high in relation to weight. You may need to switch to basal bolus regimen for him is what I feel. We have tried small doses of Metformin in some of these patients and had improvement in control. Although there is not much evidence on such use of Metformin. Ofourse consider iron chelation and discussion with the hematology team. Hope this helps. All the best.