I am surprised how can the doctor prescribe but leave the use to your decision. I have done the same research few weeks back about tamiflu in pregnancy. the company that makes Tamiflu says the drug has nnot been studied well enough in pregnant woemn. Basically that means they dont know what will be effect of the drug on unborm baby, Like many other drug, it is given a pregnancy category C, which means if it is really really necessary for mom's health, it can be given. In your wife's case, since the flu test has come negative, u should probably avoid the drug unless she looks really sick. What r her symptoms like..??