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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Trying To Get Pregnant. Taking Duphaston. No Periods. Why?

Hi I am a 29 year old married girl. I have irregular menstrual cycles from long back. I am currently trying to get pregnant and visited one Gynecologist. She prescribed me Duphaston 10 mg from 16th Day to 25th day of my cycle with 2 tablets a day. I have started the tablet from last month on 17th April 2013 and ended on 26th April, 2013. But till date I have not got periods. Could you please explain. Last month I had periods on 2nd April, 2013
Tue, 7 May 2013
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General & Family Physician,  's  Response
Hello & thank you for posting on HCM
Duphaston is synthetic derivation of naturally occuring hormone (progeterone) - which is predominantly secreted by ovaries to help maintain & thicken linng of uterus to support implantation & subsequent pregnancy.
As your last period was 2nd april & you had taken tablets from 17th to 26th (i.e D15 to D24 of cycle) - it was correct regime, if implantation had not happened - within 2-3 days of stopping duphaston you would normally start periods if you are not pregnant.
But if implantation & subsequent pregnancy has happened - periods will not come after stopping duphaston (interval of 2-4 days) & in that caes I suggest you must take home preg test first.
There is another possibility where stopping duphaston may not start periods ( this is normally due to lack of estrogen in the first of half of cycle) but to diagnose this one needs to have progesterone challenge for 1-2 cycles & also USS for ovarian tracking.
Hope this is helpful
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Trying To Get Pregnant. Taking Duphaston. No Periods. Why?

Hello & thank you for posting on HCM Duphaston is synthetic derivation of naturally occuring hormone (progeterone) - which is predominantly secreted by ovaries to help maintain & thicken linng of uterus to support implantation & subsequent pregnancy. As your last period was 2nd april & you had taken tablets from 17th to 26th (i.e D15 to D24 of cycle) - it was correct regime, if implantation had not happened - within 2-3 days of stopping duphaston you would normally start periods if you are not pregnant. But if implantation & subsequent pregnancy has happened - periods will not come after stopping duphaston (interval of 2-4 days) & in that caes I suggest you must take home preg test first. There is another possibility where stopping duphaston may not start periods ( this is normally due to lack of estrogen in the first of half of cycle) but to diagnose this one needs to have progesterone challenge for 1-2 cycles & also USS for ovarian tracking. Hope this is helpful