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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Ultrasound Has Ovarian Tumor. Can Endometriosis Cause A High CA125 Reading?

I was found to have a 17 cm x 12 cm x 10 cm ovarian tumor during an ultrasound on Tuesday. I just got my CA-125 test results today which read a 334. Can endrometriosis (which I have had my entire life) cause a reading this high? I am 60 yrs old, healthy, no pain, no other symptoms and all other blood tests and PAP test cam back normal. I have two CT scans scheduled for the am. I am worried sic but praying this tumor is benign. Any thoughts on the CA125 test results?
Wed, 16 Jan 2013
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General Surgeon,  's  Response
Hi.CA 125 is elevated not only in Ovarian cancers but also in other cancers like endometrial cancer,fallopian tub cancer,breast cancer etc.It is also raised in Non cancerous conditions like Endometriosis,several diseases of the ovary like Ovarian cyst etc.As per literature,only 3% of females with raised CA125 levels have Ovarian cancer.But,you should be further evaluated.Hope the Swelling in the Ovary is a benign one,not cancerous.All the best.I can follow if you post the CT reports too.Take care.
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Ultrasound Has Ovarian Tumor. Can Endometriosis Cause A High CA125 Reading?

Hi.CA 125 is elevated not only in Ovarian cancers but also in other cancers like endometrial cancer,fallopian tub cancer,breast cancer etc.It is also raised in Non cancerous conditions like Endometriosis,several diseases of the ovary like Ovarian cyst etc.As per literature,only 3% of females with raised CA125 levels have Ovarian cancer.But,you should be further evaluated.Hope the Swelling in the Ovary is a benign one,not cancerous.All the best.I can follow if you post the CT reports too.Take care.