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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Uncontrollable Laughter. Taking Cymbalta For Depression. Any Link Between These Two?

Last Saturday night as I tried to fall asleep, uncontrollable laughter took over my mind. I wasn't thinking of any funny happenings or humorous anecdotes. Each time I got out of bed the laughter subsided, however quickly returned. I must say my wife thought it was amazing. I am taking Cymbalta for depression, so this occurrence is even more baffling to me. This is the only time I can recall this happening. Is there a link between depression and this sudden outburst of laughter?

Thu, 22 Aug 2013
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Psychiatrist 's  Response
Sudden laughter burst during initial period of sleep can occur in "gelastic epilepsy" (a type of seizure disorder).

But such episodes can occur in depressive phase also, particularly, if depression is severe. Such symptoms are called "dissociative episodes"

Doing an EEG (electroencephalography) by consulting a neurologist will help to come to a diagnosis

You should discuss about this episode with treating psychiatrist
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Uncontrollable Laughter. Taking Cymbalta For Depression. Any Link Between These Two?

Sudden laughter burst during initial period of sleep can occur in gelastic epilepsy (a type of seizure disorder). But such episodes can occur in depressive phase also, particularly, if depression is severe. Such symptoms are called dissociative episodes Doing an EEG (electroencephalography) by consulting a neurologist will help to come to a diagnosis You should discuss about this episode with treating psychiatrist