HealthCareMagic is now Ask A Doctor - 24x7 | https://www.askadoctor24x7.com

Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties
159 Doctors Online

By proceeding, I accept the Terms and Conditions

Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

HCM Blog Instant Access to Doctors
HCM BlogQuestions Answered
HCM Blog Satisfaction

What Are The End Stage Symptoms Of Diffuse B Cell Lymphoma Stage 4B?

My daughter has diffuse b cell lymphoma stage 4b, treatment with r chop disease progressed, treatment with r GDP, treatment progressed to cns, treatment with high dose methotrexate has reduced cns cancer but systemic cancer is now growing again. She is 29 years old and will be starting chap next week for 2 cycles and then ?final restaging to determine if strictly palliative care is the only option. What end stage symptoms should we expect?
Tue, 30 Jun 2015
Report Abuse
Pulmonologist,  's  Response
Thanks for your question on Health Care Magic.
I can understand your daughter's situation and problem.
Diffuse B cell lymphoma is very rapidly progressive in almost all lymphnodes in the body.
It causes lymphnode enlargement and obstruction in the lymphatic channel.
So end stage symptoms can be bilateral lower limb lymphedema, superior vena cavalry syndrome (puffiness of face and breathlessness), weight loss, weakness, anorexia, breathlessness due to Pulmonary embolism and lung metastasis etc.
Opportunistic infections are also common due to lower immunity. So tuberculosis, fungal infection etc are common in end stage of disease.
Hope I have solved your query.
I will be happy to help you further.
Wishing good health to your daughter.
Thanks.
I find this answer helpful
Note: For further queries related to kidney problems Click here.
Disclaimer: These answers are for your information only and not intended to replace your relationship with your treating physician.
This is a short, free answer. For a more detailed, immediate answer, try our premium service [Sample answer]
Share on
 

Recent questions on Chemotherapy regimens


Loading Online Doctors....
What Are The End Stage Symptoms Of Diffuse B Cell Lymphoma Stage 4B?

Thanks for your question on Health Care Magic. I can understand your daughter s situation and problem. Diffuse B cell lymphoma is very rapidly progressive in almost all lymphnodes in the body. It causes lymphnode enlargement and obstruction in the lymphatic channel. So end stage symptoms can be bilateral lower limb lymphedema, superior vena cavalry syndrome (puffiness of face and breathlessness), weight loss, weakness, anorexia, breathlessness due to Pulmonary embolism and lung metastasis etc. Opportunistic infections are also common due to lower immunity. So tuberculosis, fungal infection etc are common in end stage of disease. Hope I have solved your query. I will be happy to help you further. Wishing good health to your daughter. Thanks.