Hi Thanks for choosing HCM for your query. I appreciate your concern towards the safety of Penderm plus cream. Following side effects are seen with the use of Penderm plus cream: Pimples, photosensitivity, skin thinning and telangiectasias (abnormal growth and enlargement of the blood vessels on the face), abnormal facial hair growth (cosmetic problem in females). It contains a strong and potent steroid which should never be used as a fairness cream. It must be stopped at the earliest. You may use one of the skin lightening creams like Kojic acid, Glycolic acid, Hydroquinone, arbutin etc can be used once or twice daily to fade away the pigmentation gradually. I strongly advice you these creams are to be used under dermatological guidance only. Hope this answers your query. Take care of your skin, Drink lot of water, eat fresh fruits, avoid excess sweets and fatty meals. Regards.