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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes IgM Protein Deficiency?

Hi, may I answer your health queries right now ? Please type your query here...My mother was recently told she had IGM protein deficiency and is undergoing infusions. What causes this deficiency? Is this deficiency hereditary? Should I be tested for it? Thanks,
posted on Thu, 13 Mar 2014
Twitter Wed, 15 Mar 2017 Answered on
Twitter Thu, 16 Mar 2017 Last reviewed on
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Endocrinologist,  's  Response
Hello and thanks for asking.
I have gone through your question.

Immunoglobulin M deficiency is a rare form of dysgammaglobulinemia characterized by an isolated low level of serum immunoglobulin M (IgM).
The levels of other immunoglobulin classes are within reference ranges.

Some patients are asymptomatic, whereas others develop serious infections. Patients may develop prolonged or life-threatening infections caused by bacteria and viruses, especially in infancy.

SIgM deficiency may occur as a primary or secondary condition.
Yes,this deficiency is hereditary and this means that you should be tested for it.

Hope i have answered to your questions.
If you have other questions,feel free and ask.I will be happy to help.
Take care.
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What Causes IgM Protein Deficiency?

Hello and thanks for asking. I have gone through your question. Immunoglobulin M deficiency is a rare form of dysgammaglobulinemia characterized by an isolated low level of serum immunoglobulin M (IgM). The levels of other immunoglobulin classes are within reference ranges. Some patients are asymptomatic, whereas others develop serious infections. Patients may develop prolonged or life-threatening infections caused by bacteria and viruses, especially in infancy. SIgM deficiency may occur as a primary or secondary condition. Yes,this deficiency is hereditary and this means that you should be tested for it. Hope i have answered to your questions. If you have other questions,feel free and ask.I will be happy to help. Take care.