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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Body Rash After Taking Clindamycin For Staph Infection?

I have been taking clindamycin for about 6 days now for a staph infection. I was itching my arm last night and I woke up with a rash on my arm, throughout the day i itched other areas and now I have rash on my back, face, chest, and arms. What is happening?
posted on Tue, 18 Mar 2014
Twitter Wed, 19 Mar 2014 Answered on
Twitter Wed, 19 Mar 2014 Last reviewed on
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Dermatologist,  's  Response
Hello and welcome to healthcaremagic

Definitely you have developed a Urticarial/Maculopapular drug reaction to clindamycin. I would suggest you to stop taking any further doses of clindamycin.

If I was your treating doctor I would have started you on oral antihistamines e.g Cetrizine 10mg once or twice daily. A topical soothing lotion e.g calamine lotion can be used to sooth the rashes.

Since it is most likely a drug reaction therefore we need to manage the infection with a different class of antibiotic. Macrolides e.g Azithromycin or Erythromycin cover staph. and also have the least chances of a drug reaction and can be safely substituted for clindamycin.

regards

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What Causes Body Rash After Taking Clindamycin For Staph Infection?

Hello and welcome to healthcaremagic Definitely you have developed a Urticarial/Maculopapular drug reaction to clindamycin. I would suggest you to stop taking any further doses of clindamycin. If I was your treating doctor I would have started you on oral antihistamines e.g Cetrizine 10mg once or twice daily. A topical soothing lotion e.g calamine lotion can be used to sooth the rashes. Since it is most likely a drug reaction therefore we need to manage the infection with a different class of antibiotic. Macrolides e.g Azithromycin or Erythromycin cover staph. and also have the least chances of a drug reaction and can be safely substituted for clindamycin. regards