Costochondritis, also known as Tietze’s syndrome, is an inflammation of the cartilage in the rib cage. The condition usually affects the cartilage where the upper ribs attach to the breastbone (sternum), an area known as the costosternal joint.Chest pain caused by costochondritis can range from mild to severe. Primary biliary cirrhosis is considered an autoimmune disease, in which the body turns against its own cells The bile ducts in your liver are slowly destroyed. Bile, a fluid produced in your liver, plays a role in digesting food and helps rid your body of worn-out red blood cells, cholesterol and toxins. The costochondritis does not cause PBC but it might be associated with it. When costochondritis is associated with liver disease, it is more difficult to treat. So take care and the relevant specialists will advice you further. Thank you Dr.Jolanda Pulmonologist