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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Difficulty In Swallowing When Diagnosed With Amyloidosis?

my dad was dx with mm and amylodosis in march 2014. he has had 3 blood transfussions since and now has amylodisis in his throat which tumor is pressing on his esophagus preventing him from eating or swallowing. he has been on peg tube for almost 2 months and oncologist is changing his revlimid to a different chemo treatment. what do you think is his life expectancy?
posted on Fri, 25 Jul 2014
Twitter Mon, 20 Jul 2015 Answered on
Twitter Mon, 20 Jul 2015 Last reviewed on
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Radiologist,  's  Response
Hi,
Thanks for writing in.

Amyloidosis is an autoimmune disease which affects various organs. It causes deposition of amyloid material and this is abnormal. The esophagus is the food pipe which connects the throat to stomach.

Your father might be having wall thickening in the esophagus which is causing the sensation of difficulty in swallowing also called dysphagia.

Many patients respond to dysphagia with steroids and chemotherapy. The survival rate at 2 and 4 years was 84% and 72%, respectively in a research study for gastrointestinal amyloidosis. Please do not worry.
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What Causes Difficulty In Swallowing When Diagnosed With Amyloidosis?

Hi, Thanks for writing in. Amyloidosis is an autoimmune disease which affects various organs. It causes deposition of amyloid material and this is abnormal. The esophagus is the food pipe which connects the throat to stomach. Your father might be having wall thickening in the esophagus which is causing the sensation of difficulty in swallowing also called dysphagia. Many patients respond to dysphagia with steroids and chemotherapy. The survival rate at 2 and 4 years was 84% and 72%, respectively in a research study for gastrointestinal amyloidosis. Please do not worry.