What Causes Elevated ALT And AST Levels?

Hi, I m a 43 yr old female and I ve NEVER had any previous liver issues in the past. My AST level has always ranged from 24-27 and ALT ranged 14-16. Unfortunately, I had a positive TB Quantiferon showed Latent TB exposure which I was then given ISONIAZID to take for six months. My rheumatologist informed me that my AST now 116 and my ALT is 114. I ve lost about 12 lbs, poor appetite and have recently had a low grade temp no higher than 99.8. Now I m expecting upper (thorasic) back pain which I ve never experienced before. Just to add, I also suffer with Systemic Lupus, Sjogren s Syndrome, Trigeminal Neuralgia, Raynauds and other carry-on issues from those illments. How concerned should I be, if any? I m asking you because I no longer work or have insurance, therefore, most of my medical care is out-of-pocket and I recently became a beneficiary of county benefits , it may take some time before I can see a specialist. Any information will be appreciated. Thanks