Hello dear I understand your concern CRP is acute pahse reactant protein and increase in body response to inflammation. It increased level suggests so many inflammatory disease. Following are the causes of increased CRP: Cancer, increased risk of the cardiovascular disease and hypertension, diabetes,metabolic syndrome Scleroderma, polymyositis, and dermatomyositis Any chronic inflammatory disase Rheumatoid arthritis. So it is difficult to say only from high CRP value about leukemia. It usually diagnosed from the blood picture and from clinical symptoms. Hope this may help you Contact HCM for further health query Best regards Dr. Sagar