Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties
159 Doctors Online

By proceeding, I accept the Terms and Conditions

Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

HCM Blog Instant Access to Doctors
HCM BlogQuestions Answered
HCM Blog Satisfaction

What Causes Elevated Liver Enzymes While On Chemotherapy?

Doing well Now 6 weeks on Ceritinib for stage IV NSCLC with some bone and marrow involvment. dx 2/15/14 alk pos.previous tx crizotinib 22month before progression, I am chemo; radiation naive; had total hyst for adenocarcinoma 1 year after dx 9/1011 T1A ... Labs from 8/4/14 liver enzymes starting to rise..ast 72, alt 78, Alk phos 372....new this last month immature granulocyte .90 absolute .10. neuts 77.8 lymps 11.5, absolute neuts 8.8 absolutes monocytes 0.7. labs taken at tail end of a week long virus..fever 101, cough malaise...now resolved. Cerritinib is more toxic but doing well in general...ca125 860 six weeks ago now 44. WBC 11.2 should I be concerned for any underlying other issues? thanks CJD
posted on Fri, 15 Aug 2014
Twitter Sat, 2 Nov 2019 Answered on
Twitter Thu, 7 Nov 2019 Last reviewed on
Report Abuse
General Surgeon,  's  Response
Hi,

SGOT and SGPT are sensitive indicators of liver damage or injury from different types of diseases or conditions, and collectively they are termed liver tests or liver blood tests.

So the next step is to look for certain liver damage and most common casue is fatty liver disease.

It should be confirmed by ultrasound. Other causes are viral hepatitis, cirrhosis, medications, alcohol intake or autoimmune diseases.

To verify exact cause, US, bilirubin levels and tumor markers should be additionally done Then appropriate treatment can be started.

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr Iven Romic Rommstein, General Surgeon
I find this answer helpful
Note: For further follow up on digestive issues share your reports here and Click here.
Disclaimer: These answers are for your information only and not intended to replace your relationship with your treating physician.
This is a short, free answer. For a more detailed, immediate answer, try our premium service [Sample answer]
Share on
 

Related questions you may be interested in


Loading Online Doctors....
What Causes Elevated Liver Enzymes While On Chemotherapy?

Hi, SGOT and SGPT are sensitive indicators of liver damage or injury from different types of diseases or conditions, and collectively they are termed liver tests or liver blood tests. So the next step is to look for certain liver damage and most common casue is fatty liver disease. It should be confirmed by ultrasound. Other causes are viral hepatitis, cirrhosis, medications, alcohol intake or autoimmune diseases. To verify exact cause, US, bilirubin levels and tumor markers should be additionally done Then appropriate treatment can be started. Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr Iven Romic Rommstein, General Surgeon