Hi Thanks for posting on HCM Excessive weight may not be due to these drugs.These drugs are anti-hypertensive drugs.Amiodarone being an anti-arythmic and bystolic a beta blocker.These drugs will not be prescribed to you if they have as side effect excess weight gain as the first step to fighting hypertension is weight control. You gain weight when you eat more than you work, that is, when energy you receive from food is more than what you use for your activities.The excess energy will be stored in the form of proteins in muscle and fats in adipose tissues.Stopping your drugs may instead cause you more problems.I will advise you try the following: -Exercise regularly -Eat only when hungry -Eat in small quantities and balanced -Take more of fruits and vegetables You will also need to see your Doctor or a Cardiologist for evaluation.A lipid profile test will be very useful to you to see if you will be in need of a statin group of drugs. Hope my answer will help you Best regards