I was diagnosed with TTP in December 2013 and had a platelet count of 12 I was given a plasma exchange for 5 days and responded well and have had a good platelet count since. My problem though has been since the diagnosis I ve suffered from extreme tiredness and pain in my limbs. I ve also got arthritis in most of my joints and have had since I was 21 I m now 45 but the pain has increased significantly since the TTP is there a link with TTP and this kind of pain? I also suffer from EHS which has become more regular.