Hello,
Weakness of muscles to the point you can't stand up is called proximal myopathy. The following are few causes of proximal myopathy:
1) Diabetes
2) Inflammatory: polymyositis /
dermatomyositis. NB: can overlap with other
connective tissue disease eg. mixed connective tissue disease. Other connective tissue disease eg. SLE, vasculitis, RA,
systemic sclerosis.
3) Cancer (paraneoplastic: carcinomatous neuromyopathy)
4) Drugs (statins, steroids)
5) Infections (bacterial infections, CMV, EBV, hepatitis)
6) Endocrine (thyroid, Addison's, osteomalacia, Cushing's, acromegaly, diabetic amyotrophy)
7) Toxins (alcohol)
8)Metabolic (renal / liver failure, electrolyte disturbance)
9) Miscellaneous (
inclusion body myositis, rhabdomyolysis, sarcoidosis, mitochondrial myopathy, muscular dystrophy)
You need to be examined in detail in person and few investigations like liver function tests,
thyroid function tests, blood tests including counts, rheumatology tests etc. Please do consult a physician for a specific diagnosis and appropriate treatment.
Take care. Hope I have answered your question. Let me know if I can assist you further.
Regards,
Dr. Pallavi M., Anesthesiologist