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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Fatigue And Loss Of Appetite While Having Myeloma?

Would appreciate your opinions on the possible cause of sudden severe fatigue, loss of appetite, weight loss, dryness in mouth & lips, belching - all occurring 3-4 months after a stem cell transplant for multiple myeloma. Tests are negative - numbers/readings as a result of the transplant are good. These symptoms just started about 2 weeks ago. The only test result we are waiting for is a
thyroid test. My biggest concern is the sudden and extreme fatigue and lack of appetite. I am 65, about 5'5" and 142 lbs. About 9 years ago I was diagnosed with multiple myeloma and given about 6 months to live. Since then, I've managed the disease with chemo and other drugs, and two stem cell transplants.
Wed, 18 Mar 2015
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Pulmonologist,  's  Response
Hello dear, thanks for your question on HCM.
I can understand your situation and problem.
In my opinion following are the possibilities for your symptoms.
1. Side effects of chemotherapy and immunosuppressive drugs.
2. Chronic infection.
Chemotherapy and immunosuppressive drugs are very toxic to the normal healthy cells of the body. So they show many side effects. So your symptoms might be due to side effects.
Another possibility is opportunistic infections. These drugs lower the immunity and make patient prone to infections.
So discuss these two possibilities with your oncologist and start appropriate treatment.
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What Causes Fatigue And Loss Of Appetite While Having Myeloma?

Hello dear, thanks for your question on HCM. I can understand your situation and problem. In my opinion following are the possibilities for your symptoms. 1. Side effects of chemotherapy and immunosuppressive drugs. 2. Chronic infection. Chemotherapy and immunosuppressive drugs are very toxic to the normal healthy cells of the body. So they show many side effects. So your symptoms might be due to side effects. Another possibility is opportunistic infections. These drugs lower the immunity and make patient prone to infections. So discuss these two possibilities with your oncologist and start appropriate treatment.