Within the past 18 months I ve had two knee replacements, shoulder scope with rotator cuff repair, 3 UTI s, Strep throat, extreme fatigue and loss of weight. My skin has become glossy and extremely wrinkled. I was forced to retire. I was a home health RN and extremely sleep deprived. My latest knee is still painful. My main exercise is taking care of my house, walking my dogs one mile a day, regardless. I ve exhausted ALL of my PT, can t have any Oxycodone because of Oklahoma laws. The Codeine doesn t work with the pain or sleep. I have a history of HTN and arthritis. Because I hobbled around with bad knees for so long my L5 is slipping. My biggest complaint is inability to sleep. I have chronic sinus drainage and knee pain in the night. My bladder is dropping so I have to get up about 0400 to urinate and can t go back to sleep. I am always exhausted.