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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Hallucinations And Confusion While On Hydrobromide And Lyrica?

I am very concerned about my mom. She is seeing things that aren t there. Hallucinating, cofusion, forgetfulness, drowsy, lack of coordination. She is taking 600 mg of LYRICA , 40mg of CITALOPRAM hydrobromide, and 80 mg of OXYCODONE daily. Along with her blood pressure meds and diabetic meds. Is this a normal side effect? Should she be taken to EAR?
Wed, 30 May 2018
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General & Family Physician,  's  Response
Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice.

Suggestive of serotonin syndrome. I've gone through your query and I appreciate your concerns for your beloved mother. Taking Oxycodone together with Citalopram hydrobromide can increase the risk of a serious condition called the serotonin syndrome which is characterized by confusion, hallucination, seizure, increased blood pressure and heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremor, motor incoordination, vomiting, and diarrhea. In its severe form it may result in coma and even death. This is not a normal side effect so she should be taken to ER immediately for further evaluation and treatment. While taking Citalopram or Oxycodone together with Lyrica may increase side effects such as dizziness, drowsiness, confusion, difficulty concentrating, impaired thinking, judgment, and motor coordination. She may need dose adjustment or alternate effective drugs to minimize the risk of the above side effects.

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What Causes Hallucinations And Confusion While On Hydrobromide And Lyrica?

Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. Suggestive of serotonin syndrome. I ve gone through your query and I appreciate your concerns for your beloved mother. Taking Oxycodone together with Citalopram hydrobromide can increase the risk of a serious condition called the serotonin syndrome which is characterized by confusion, hallucination, seizure, increased blood pressure and heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremor, motor incoordination, vomiting, and diarrhea. In its severe form it may result in coma and even death. This is not a normal side effect so she should be taken to ER immediately for further evaluation and treatment. While taking Citalopram or Oxycodone together with Lyrica may increase side effects such as dizziness, drowsiness, confusion, difficulty concentrating, impaired thinking, judgment, and motor coordination. She may need dose adjustment or alternate effective drugs to minimize the risk of the above side effects. Hope I have answered your query. Let me know if I can assist you further.