HealthCareMagic is now Ask A Doctor - 24x7 | https://www.askadoctor24x7.com

Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties
159 Doctors Online

By proceeding, I accept the Terms and Conditions

Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

HCM Blog Instant Access to Doctors
HCM BlogQuestions Answered
HCM Blog Satisfaction

What Causes Intense Back Pain Despite Taking Fentanyl For Herniated Disc On L4?

Just started fentanyl 12 much yesterday morning.The Pharmacist told me that I may experience more pain to start with and he was right.A lot of pain last night and today.The dose will go up every 3rd day. My question is this is a pain killer, why even if it is a low dose that I should hurt more. Very bad lower back due to herniated disc sitting on L4 nerve, facet arthritis,Osteoarthritis.Degeneration disc desease,Stenosis of the whole cervical spine Fibromyalgia,Meds Neurontin- Nortriptallyn, Tylenol for arthritis,zopiclone for sleep.Highly sensitive to loads of meds
Wed, 11 Sep 2019
Report Abuse
General Surgeon,  's  Response
Hello,

* Poor response to Fentanyl can be part of multiple issues as

- tolerance from the previous usage

- receptor down-regulation which makes receptor less likely to respond to Fentanyl

- pathological load of disc compression overweights the analgesic benefits

- underlying stress, anxiety and uneasiness may be part of other autos immune-related conditions to be evaluated with expert neurologist does

- exacerbating factors as liver P 450 levels, co-prescription of many of the molecules.

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr Bhagyesh V. Patel, General Surgeon
I find this answer helpful
Note: For further follow up on related General & Family Physician Click here.
Disclaimer: These answers are for your information only and not intended to replace your relationship with your treating physician.
This is a short, free answer. For a more detailed, immediate answer, try our premium service [Sample answer]
Share on
 

Related questions you may be interested in


Loading Online Doctors....
What Causes Intense Back Pain Despite Taking Fentanyl For Herniated Disc On L4?

Hello, * Poor response to Fentanyl can be part of multiple issues as - tolerance from the previous usage - receptor down-regulation which makes receptor less likely to respond to Fentanyl - pathological load of disc compression overweights the analgesic benefits - underlying stress, anxiety and uneasiness may be part of other autos immune-related conditions to be evaluated with expert neurologist does - exacerbating factors as liver P 450 levels, co-prescription of many of the molecules. Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr Bhagyesh V. Patel, General Surgeon