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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Leg Cramps While On Spironolactone And Synthroid?

High blood pressure, type 2 diabetes. Take Synthoid, Spironolactone,Glyburide,Lisinopril (25/20) Atenelol,Metformin., Amlopodine (Norvasc). Spironolactone is only new one recently added. Since taking these meds, am having intense night cramps on legs and feet. Is this a side affect of one of these meds? Will increasing water intake adviseable to get rid of cramps?
posted on Thu, 8 Dec 2016
Twitter Wed, 14 Dec 2016 Answered on
Twitter Wed, 14 Dec 2016 Last reviewed on
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General & Family Physician,  's  Response
Hello dear,
I understand your concern. Spironolactone is a Potassium channel diuretic. It may rise your serum potassium level which may be the cause of your muscle cramps.You have to check your serum sodium, potassium levels.If the serum potassium is high you have to reconsider the spironolactone.
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What Causes Leg Cramps While On Spironolactone And Synthroid?

Hello dear, I understand your concern. Spironolactone is a Potassium channel diuretic. It may rise your serum potassium level which may be the cause of your muscle cramps.You have to check your serum sodium, potassium levels.If the serum potassium is high you have to reconsider the spironolactone. Thank you