Hello; thanks for the query. Presently, elevated creatinine levels & symptoms described appear unrelated. Though you should consult a Nephrologist for a detailed evaluation & treatment for elevated serum creatinine levels. The symptoms you are described can occur both in acute exacerbation of cardiac angina and during panic attacks. While panic attacks are relatively benign & easy to treat; angina misdiagnosed & ignored can be fatal. Hence, rule out any cardiac cause by doing blood cholesterol, ECG, Stress ECG testing (Bruce protocol) & other tests as relevant/advised by doctor. Once these are ruled out; we can do a detailed evaluation of her panic attacks. If these are indeed anxiety/panic attacks; then we can use SSRI drugs like sertraline, paroxetine, escitalopram etc. along with rapid relief sos anxiolytics like clonazepam, etizolam etc. These along with certain relaxation techniques (deep breathing) can take care of her trobles very quickly. Do revert back for any further help. Good luck