Welcome to HCM, I would love to give you an accurate answer and I will give you my best answer, but when you write in please provide essential details as to your case including lab values, diagnosis, supplement use. What is see is possible osteoporosis, which, if present should be evaluated by a specialist. I see too many people put on the wrong medication with serious side-effects. Bisphosphonates are often prescribed when it is the injectable drug they need. Get the test for the proper medication. If osteoporosis is one of the diagnosis and you are asking about pain and breaking bones, try to support your skeletal structure with the following: Make sure you re getting adequate calcium and vitamin D, Vitamin D is now being recognized as a key player in osteoporosis. Even though patients are taking calcium plus D, they may not be getting enough D. They may need prescription vitamin D -- it s that important. according to the specialists. In fact, even when you start taking osteoporosis medicine, it s critical to keep getting these supplements, a postmenopausal woman needs 1,500 milligrams calcium daily, plus 1,000 units of vitamin D. Some need prescription-strength vitamin D [Calcitriol]. This deficiency is a serious problem. Also critical: Do weight-bearing exercise, don t smoke, and if you drink alcohol, drink moderately. I understand weight bearing may be difficult, suggest you consult a physical therapist and get weight bearing exercises prescribed for pool therapy. Your case sounds far more complicated than you are portraying. The anemia you profess to is more than likely anemia of chronic disease compounded by iron deficiency. Does the IV increase your ferritin, hemoglobin or blood iron after 3 months post treatment? If not, it is not doing you any good. Find the reason you aren t absorbing iron. If you are already on calcium I will tell you that calcium and iron do not get along at all. Calcium will inhibit the absorption of iron so son t take the day of the infusion or with supplements or with iron containing foods. Fortified cereals, use almond milk. If you had given me all your lab values I could tell you more about your iron status. I would consider at least one multivitamin taken at a different time than any medications if not contraindicated. Do you tolerate the small amount of iron in a multivitamin as some don t. I can provide additional consultation through the specialty port, ask for me and include all information including medication, diagnoses, diet order, what you typically eat, supplements and I will see what more I can suggest in this type of situation. Healthy Regards, Kathryn Shattler, MS,RDN