Hello! Thank you for asking on HCM! I understand your concern and would explain that swelling is not typically associated to mitral valve prolapse. But it may be related to a low cardiac function or other disorders such as: - kidney impairment - liver impairment - long periods of standing up and lack of physical activity - venous insufficiency in the inferior limbs - some drugs (calcium channel blockers, etc.) could also be the cause. I recommend consulting with your GP for a careful physical examination and some tests: - a resting ECG and cardiac ultrasound to examine the cardiac function - a Doppler ultrasound of the inferior limbs - some blood lab tests (complete blood count, kidney and liver function tests, PCR, sedimentation rate, blood electrolytes, blood osmolarity, etc.) You should discuss with your doctor on the above issues. Hope to have been helpful! Best wishes! Dr. Iliri