I have been on allopurinol for apx. 2 weeks and noticed a rash on my entire body (including legs, feet, arms, hands) starting about three days ago. I suspected that it could be this drug. I am taking it as a result of a severe case of gout occurring at the beginning of july. I feel that I will discontinue taking this drug and contact my primary care physician on Monday. I only wonder if I can just quit...or is any type of weaning process necessary? taking a 300mg tablet once per day. Also, is it acceptable to take an antihistamine, ie, Benadryl?