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Dr. Andrew Rynne
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Dr. Andrew Rynne

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What Causes Recurrent Hives Despite Taking Methylprednisolone?

My daughter who has had a sinus infection for several days went to her MD Thursday for hives and was given a prescription for Methylprednisolone 4mg to be taken in tapering daily doses. She was directed to take 6- 4mg. tabs at once on Thursday given she saw the MD at the end of the day. Yesterday her skin cleared up. But today the hives returned far worse. She went to Urgent Care today and the MD gave her a prescription for Prednisone. My questions: 1: Couldn t the Methylprednisolone have triggered an increase in the hives and 2: Since Prednisone must first be metabolized to its active form methyprednisolone what is to rationale for prescribing Prednisone.
Fri, 27 Apr 2018
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Dermatologist,  's  Response
Hello and Welcome to ‘Ask A Doctor’ service.
I have reviewed your query and here is my advice.

As per your case history of Urticaria, my treatment advice is -
1. Avoid fast food and food with artificial colours for 2 months.
2. Apply a soothing lotion like calamine lotion on affected region twice daily.
3. Take an antihistamine medication like Levocetrizine twice daily for 7-10 days.
4. Other treatment options are oral steroid, Hydroxyzine taken only after consulting a dermatologist.

I hope I have answered your query. Let me know if you have any further questions.
Regards,
Dr. Harshit Bhachech.
MBBS, DDVL.
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What Causes Recurrent Hives Despite Taking Methylprednisolone?

Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. As per your case history of Urticaria, my treatment advice is - 1. Avoid fast food and food with artificial colours for 2 months. 2. Apply a soothing lotion like calamine lotion on affected region twice daily. 3. Take an antihistamine medication like Levocetrizine twice daily for 7-10 days. 4. Other treatment options are oral steroid, Hydroxyzine taken only after consulting a dermatologist. I hope I have answered your query. Let me know if you have any further questions. Regards, Dr. Harshit Bhachech. MBBS, DDVL.