Hello, I understand your concern. I am Dr Arun Tank, Infectious diseases specialists, responding to you. Usually jockey itch respond to antifungal drugs quickly. There are two reason for unresponsiveness first is the resistance of fungus to drugs, second is some underlying disease which is favouring the growth of fungus. I suspect some underlying disease in you like diabetes, HIV, or some condition like sweating which favors the growth of fungus. Look after of this cause along with antifungal drugs can help you. I will be glad to answer your further query. Thank you for your contact to health care magic. Wish you a best health. Thank you, Dr Arun Tank.