OK. I took my first zonisamide 100 mg capsule at about 2:30 this afternoon. By 7 p.m. I have a very nice very pink, not yet tomato red, rash* across my chest from shoulder to shoulder and from my neck down to my solar plexus. * The rash is fairly solid. The zonisamide is being tried to replace divalproex (for seizures) which has contributed to some behavioral problems which are pretty much under control. And I got a good - and increasing - rash a couple of weeks ago to lamotrigine. I am at 5oo mg/day of the divalproex.