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Dr. Andrew Rynne

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What Causes Restless Leg Syndrome While On Gabapentin?

Hi, I take gabapentin 300 mg - 3 times daily. I had been out for a week or so - had the prescription filled yesterday but had in the mean time taken 2 Tylenol arthritis tabs - I have restless leg syndrome. I didn't sleep all night or since today. Legs really jerky and cramping! Please advise!
posted on Wed, 17 Feb 2016
Twitter Tue, 15 Mar 2016 Answered on
Twitter Tue, 15 Mar 2016 Last reviewed on
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Dentist,  's  Response
Hi Dear,

Welcome to HCM.

Understanding your concern. As per your query you have restless leg syndrome while on Gabapentin . Well there can be many reasons for symptoms you mention in query like nerve compression , neuropathy , DVT , muscle spasm or multiple Sclerosis , but in your case the symptoms is due to restless leg syndrome which is a neurological disorder. If condition doesn't get well then consult orthopedic surgeon as well as psychiatrist for proper examination. Doctor may prescribe methotrexate , anti inflammatory long with nerve supplement and recommend physical therapy . Along with that doctor may also prescribe antiepileptic drug I would suggest you to do light stretching exercises along with gentle massage , apply warm compresses on entire leg and take muscle relaxants like orthodox MR . Do not sit or stand for long time in one position , do yoga , meditation , avoid alcohol and caffeinated products and keep your legs in hot water tub with Epsom salt for 15 minutes. If condition doesn't get well then consult orthopedic surgeon as well as psychiatrist for proper examination.

Hope your concern has been resolved.

Get Well Soon.

Best Wishes,
Dr. Harry Maheshwari
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What Causes Restless Leg Syndrome While On Gabapentin?

Hi Dear, Welcome to HCM. Understanding your concern. As per your query you have restless leg syndrome while on Gabapentin . Well there can be many reasons for symptoms you mention in query like nerve compression , neuropathy , DVT , muscle spasm or multiple Sclerosis , but in your case the symptoms is due to restless leg syndrome which is a neurological disorder. If condition doesn t get well then consult orthopedic surgeon as well as psychiatrist for proper examination. Doctor may prescribe methotrexate , anti inflammatory long with nerve supplement and recommend physical therapy . Along with that doctor may also prescribe antiepileptic drug I would suggest you to do light stretching exercises along with gentle massage , apply warm compresses on entire leg and take muscle relaxants like orthodox MR . Do not sit or stand for long time in one position , do yoga , meditation , avoid alcohol and caffeinated products and keep your legs in hot water tub with Epsom salt for 15 minutes. If condition doesn t get well then consult orthopedic surgeon as well as psychiatrist for proper examination. Hope your concern has been resolved. Get Well Soon. Best Wishes, Dr. Harry Maheshwari