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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Retrograde Ejaculation Despite Taking Clozapine?

Dr. Rynne, I have retrograde ejaculations. I think it was because I was taking the medication clozapine; which I have stopped about a year ago. Can you recommend treatment options for me to return to regualar ejaculations. I am 68 years old and still have sex and matubate. My partner says she miss the pleasure of feeling my burst of semen during orgasm and I miss seeing it; too! Answer on YYYY@YYYY Waiting to hear from you, On-tee
Wed, 27 Apr 2016
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General & Family Physician,  's  Response
Hi,
Thanks for posting in HCM.
I understand your concern.
Retrograde ejaculation occurs when semen, which should be ejaculated via urethra, is redirected to the urinary bladder.
Normally, the sphincter of the bladder contracts before ejaculation forcing the semen to exit via the urethra. But, when the bladder sphincter does not function properly, retrograde ejaculation occurs.
Various causes that could cause this problem include:
1. Autonomic nervous system dysfunction.
2. Trans-urethral resection of prostate.
3. High blood pressure.
4. Benign prostate hyperplasia.
5. Uncontrolled diabetes mellitus.
Treatment depends on the cause. Medications like antidepressants, chlorphenamine, ephedrine and phenylephrine may work in a few cases.
Hope the information provided would be helpful.
All the best.
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What Causes Retrograde Ejaculation Despite Taking Clozapine?

Hi, Thanks for posting in HCM. I understand your concern. Retrograde ejaculation occurs when semen, which should be ejaculated via urethra, is redirected to the urinary bladder. Normally, the sphincter of the bladder contracts before ejaculation forcing the semen to exit via the urethra. But, when the bladder sphincter does not function properly, retrograde ejaculation occurs. Various causes that could cause this problem include: 1. Autonomic nervous system dysfunction. 2. Trans-urethral resection of prostate. 3. High blood pressure. 4. Benign prostate hyperplasia. 5. Uncontrolled diabetes mellitus. Treatment depends on the cause. Medications like antidepressants, chlorphenamine, ephedrine and phenylephrine may work in a few cases. Hope the information provided would be helpful. All the best.