I am a 66 year old male , moderately obese@ 224 # . I had smoked for 40 years ,but quit 7 years ago. Two years later symptoms of c.o.p.d., manifested .. After diagnosis I was placed on a inhaler(formeterol) and Spiriva. for unknown reasons after a month of prescribed use began to have severe body swelling , apparently I was holding fluid, and experiencing respiratory distress. My primary care placed me on O2 for several hours ,did blood tests and prescribed medication to assist in evacuating the fluid,as well as changing the repiratory inhaler medication to Symbicort....I was then directed to a hemocult Oconologist , who has been physically examining me for the last two years as well as countless blood tests at a minimum every 3 months ... apparently my white cell/ platelets levels make large swings up and down...The isn t any internal bleeding , no diabetes etc.... levels have ranged from 400 to a present count of 98...Now we re back to monthly testing.. The question : what can possibly be causing these wild swings?