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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Severe Stomach Pain After Taking Zofran And Prilosec?

My fiancee is having severe stomach pain following some irritation on her skin last night that seemed like an allergy to something (she s never known of any previous allergies). We went to an urgent care center earlier this afternoon and they prescribed Zofran for nausea and Prilosec. She took the medicine 2 hours ago and the pain has worsened some. We re concerned it could be something else, but have no idea what could be causing the pain in the stomach.
posted on Thu, 9 Feb 2017
Twitter Thu, 6 Dec 2018 Answered on
Twitter Wed, 12 Dec 2018 Last reviewed on
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General & Family Physician,  's  Response
Hi,

Prilosec is a proton pump inhibitor. It reduces acid production but cannot get rid of the acid already present. In some persons, it can take a few days to kick in because the acid already present needs to decrease.

It may be helpful to use a medication like Dica or tums for the first few days (along with Prilosec).

Probiotics may also help as well.

Hope I have answered your query. Let me know if I can assist you further.

Regards,
Dr. Michelle Gibson James,
General & Family Physician
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What Causes Severe Stomach Pain After Taking Zofran And Prilosec?

Hi, Prilosec is a proton pump inhibitor. It reduces acid production but cannot get rid of the acid already present. In some persons, it can take a few days to kick in because the acid already present needs to decrease. It may be helpful to use a medication like Dica or tums for the first few days (along with Prilosec). Probiotics may also help as well. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Michelle Gibson James, General & Family Physician