Welcome at HCM I have gone through your query and being your physician i completely understand your health concerns. For how long u are suffering from it? Any other associated problem? like diabetes or hypterension? Any history of TB in past or exposure to TB? What medicine u are using now? have u ever done ur ECG? Chest tightness in a smoker patient should not be taken lightly since it may points toward heart as well as lungs. In my opinion u should be seen by ur attending doctor to rule out any cardiac event plus pneumothorax too If i am ur attending physician i will get ur FBC ESR ECG and chest XRAY . after that i will be able to offer you any treatment. Second ur BP reading is also high. it need to be controlled. if u already taking any medicines there is need to review ur treatment. Ankle swelling which you have mentioned need to looked at carefully since it may be due to lungs as well as heart , after then management can be initiated. Meanwhile stay calm and use acetaminophen to relieve pain. avoid salt intake and try to quit smoking. Get well soon Hope your query is adequately addressed if you still have any feel free to ask Regards Dr Saad Sultan