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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Swelling In The Throat After Taking Amlodipine Besylate And Lisinopril-Hctz?

Husband, age 64, has high blood pressure and is taking 2 medications: Amlodipine besylate 10mg; Lisinopril-Hctz 20/25mg. This morning his throat started swelling and his voice is affected, now his lip is swelling. We thought it could be some sort of allergic reaction from unknown cause. He took a benedryl and says throat is getting better. Did not eat or drink anything unusual today. He had an insect bite on back of neck yesterday. This is Minnesota fishing opener today and he touched frozen minnows and went fishing most of the day!
Mon, 16 Mar 2020
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General & Family Physician 's  Response
Hi,

It is suggestive of allergic reaction due to insect bite however the possibility of lisinopril can not be excluded. Based on the history, your husband seems to have developed allergic reaction due to insect bite and started responding well to antihistamine Benadryl. Furthermore, the use of amlodpine and lisinopril together may also cause angioedema (swelling of the lips, throat and eyes). I advise you to consult his treating doctor to review the prescribed medication.

Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Mohammed Taher Ali, General & Family Physician
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What Causes Swelling In The Throat After Taking Amlodipine Besylate And Lisinopril-Hctz?

Hi, It is suggestive of allergic reaction due to insect bite however the possibility of lisinopril can not be excluded. Based on the history, your husband seems to have developed allergic reaction due to insect bite and started responding well to antihistamine Benadryl. Furthermore, the use of amlodpine and lisinopril together may also cause angioedema (swelling of the lips, throat and eyes). I advise you to consult his treating doctor to review the prescribed medication. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Mohammed Taher Ali, General & Family Physician