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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Swollen Ankles While On Actos, Metformin And Lisinopril?

my feet and up to my ankles are swollen as if there is liquid inside on top of my feet to toes. I thought it may be due to my taking Actos 30 mg. I started taking actos around July 22, 2016. I also take glipizide 20mg twice daily and metformin 500mg. twice daily. I also take Lovistatin20mg at night, doxasosin8 mg bedtime. magnesium 400mg twice daily,metoprol 25mg twice daily and lisinopril 40mg before breakfast. If I receive an answer today, my e-mail is YYYY@YYYY . During the day, my office e-mail is YYYY@YYYY . This is Monday thru Friday 0800to 5pm. Thankyou
posted on Sun, 9 Oct 2016
Twitter Tue, 8 Nov 2016 Answered on
Twitter Tue, 8 Nov 2016 Last reviewed on
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General & Family Physician,  's  Response
Hi & Welcome.

After having gone through the history and the prescribed medications, tablet Actos seems to be responsible for the swollen ankles and feet.

Actos (Pioglitazone) is commonly prescribed as an add on therapy for the treatment of uncontrolled type 2 diabetes mellitus.

Peripheral edema (collection of fluids in the subcutaneous tissue) is one of the important side effects of Actos causing swollen ankles and the feet.
If the treatment with Actos continues, it may cause heart failure.

I advise you to consult your treating physician for the dose reduction or to discontinuance of Actos must be considered.

Hope this will be helpful.
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What Causes Swollen Ankles While On Actos, Metformin And Lisinopril?

Hi & Welcome. After having gone through the history and the prescribed medications, tablet Actos seems to be responsible for the swollen ankles and feet. Actos (Pioglitazone) is commonly prescribed as an add on therapy for the treatment of uncontrolled type 2 diabetes mellitus. Peripheral edema (collection of fluids in the subcutaneous tissue) is one of the important side effects of Actos causing swollen ankles and the feet. If the treatment with Actos continues, it may cause heart failure. I advise you to consult your treating physician for the dose reduction or to discontinuance of Actos must be considered. Hope this will be helpful.