I am 77 and have a variety of health issues including systemic lupus, hypothyroid, elevated cholesterol, interstitial lung disease (8/15), Melanoma right eye (10/15), dvt diagnosed following fall causing buckle fracture left ramus & left thumb. While on Coumadin had episode of ischemic colitis. Now doing well except for waiting for pelvis to heal. My question is that I have had recurrent cystitis for probably 50 years and recently antibiotics don t seem to work. Also I am having more frequest spasms of urethera without other symptoms of infection. Urines were also negative at that time. Is this most likely because I ve had infections for so many years? Or because my mom had interstitial cystitis and could I have it too?