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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Vaginal Bleeding Post Metformin Withdrawal?

I had 2 early miscarriages. I have PCOS and i was on metformine 1500mg daily. When a get know about my 6 weeks pregnancy, I decide to stop the metformine as Dr advice it inorder to allow pregnancy. Then after 4 days I start havin light bleeding.At hospital the gyne do echo and found a gestational sac. On the next day there was no bleeding and the Dr allow me home and bed rest and no new Rx. So I stop the metformine. Then 3 days later I bled wittout pain.. and in echo no sac and uterine lining thin.. What happen.. should i continue metformine. Last year was same miscarriage when I stop metformine. (Is Metformine important for PCOS patients)
Mon, 7 Aug 2017
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General & Family Physician,  's  Response
Hi,
Thanks for the query. I understand your concern.
Metformin is a drug given to PCOD patients to remove insulin resistance & reduce body weight as a part of treating PCOD.
Metformin suplementation ( in suitable dose)throughout pregnancy to PCOD patients is observed to reduce possibility of abortion.
Still early fetal loss is also many a times due to deficient progesterone hormone.
* I would suggest to discuss this with your doctor & get improvised treatment during next conception./ Try conception after complete treatment of PCOD.

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What Causes Vaginal Bleeding Post Metformin Withdrawal?

Hi, Thanks for the query. I understand your concern. Metformin is a drug given to PCOD patients to remove insulin resistance & reduce body weight as a part of treating PCOD. Metformin suplementation ( in suitable dose)throughout pregnancy to PCOD patients is observed to reduce possibility of abortion. Still early fetal loss is also many a times due to deficient progesterone hormone. * I would suggest to discuss this with your doctor & get improvised treatment during next conception./ Try conception after complete treatment of PCOD. Thanks