Hi Vomiting and defecation are due to the side effects of chemotherapy. Vomiting can be treated by Ondansetron In regard to the dosing of ondansetron at a dose of 16–24 mg orally and 8–12 mg (maximum, 32 mg) Palonosetron at a dose of 0.25 mg i.v. Oral palonosetron is not yet available. Palonosetron has a significantly longer half-life and a higher binding activity than the other 5-HT3RAs. Defecation can be treated by drinking clear liquids. As soon as your diarrhea starts, switch to a diet of clear liquids, such as water, apple juice, clear broth and ice pops. Avoid milk products, as lactose intolerance may be part of your diarrhea. When you have diarrhea, you may need to drink eight to 12 cups of liquid a day. Eat low-fiber foods. As your diarrhea starts to improve, add foods low in fiber to your diet, such as bananas, rice, applesauce and toast. Eat frequent small meals. Eat foods that are high in potassium. Potassium is an important mineral that you can lose through diarrhea. Try eating bananas, potatoes and apricots to boost your potassium levels. If you have kidney problems, consult with your doctor before eating foods that are high in potassium. Avoid foods that can irritate your digestive tract. These include dairy products, spicy foods, alcohol, foods and beverages that contain caffeine, orange or prune juice, and foods high in fiber and fat. Try probiotics. Found in yogurt and dietary supplements, probiotics are beneficial bacteria that may help restore normal digestion. Lactobacillus and bifidobacterium are two examples of probiotics. If you ve had a bone marrow transplant, check with your doctor before using probiotics. Regards Dr DE