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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Vomiting And Pain From Infusions For Lukopenia?

My mother was diagnosed with Lukopenia and has been receiving monthly infusions as part of her treatment. However the last two times she's had reactions to the infusion and tonight, 1 day after her most recent infusion went to the ER vomiting and in pain from the infusion. Is this normal? What can we do? Is it possible she was mis-diagnosed?
Mon, 15 Sep 2014
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Pathologist and Microbiologist 's  Response
Hi,
Thanks for asking.
Based on your query, my opinion is as follows.
1. Leukocyte infusion can induce allergic reactions
2. The reactions is becoming more severe.
3. Leukopenia cause needs to be identified. Leukocyte transfusions is not safe always. After a period, it is going to induce reactions. Cause needs to be identified. If severe and it is pancytopenia, peripheral stem cells from you can be harvested and stem cell transplantation can be tried. Leukopenia alone is not seen usually.
Hope it helps.
Any further queries, happy to help again.
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What Causes Vomiting And Pain From Infusions For Lukopenia?

Hi, Thanks for asking. Based on your query, my opinion is as follows. 1. Leukocyte infusion can induce allergic reactions 2. The reactions is becoming more severe. 3. Leukopenia cause needs to be identified. Leukocyte transfusions is not safe always. After a period, it is going to induce reactions. Cause needs to be identified. If severe and it is pancytopenia, peripheral stem cells from you can be harvested and stem cell transplantation can be tried. Leukopenia alone is not seen usually. Hope it helps. Any further queries, happy to help again.